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Senior Scientist - Cell Line Development

Reference

32123

Sector

Life Science & Biotechnology

Salary

Competitive

Benefits

Competitive benefits package

Town/City

Edinburgh

Contract Type

Permanent

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Snr Scientist - Cell line Development (AAV)

Abercorn Sinclair is proud to partner with Asklepios Biopharmaceutical (AskBio), as they seek to appoint a new Senior cell line development to their team at the Roslin Innovation Centre, Edinburgh.

Formally Synpromics Ltd, they were formed in 2010 and quickly became recognised as a leader in the field of gene regulation. By designing and developing synthetic promoters they can regulate genes with unprecedented control, in any cell type or environmental condition.

In mid-2019, they were acquired by AskBio, one of the world’s foremost therapeutic organisations, whose founding partner pioneered the use of Adeno Associated Virus (AAV) as a viral vector.

AskBio is now a wholly owned and independently operated subsidiary of Bayer AG.

The role:

You will join the rapidly expanding R&D team to develop the next generation cell lines used to produce AAVs for Gene Therapies. The ideal candidate will have a solid grounding in virology and producer cell line development.  We are looking for Individuals with significant experience and detailed knowledge of AAV.

Skills and Experience:

  • Experience with mammalian tissue culture
  • Development of stable cell lines (ideally for viral vector production)
  • Preparation of adeno-associated virus
  • Experience with a variety of cellular and molecular biology techniques such as cloning, RT-PCR, CRISPR, assay development, etc
  • Diligent recording of data; high attention to detail; experience with ELN and databases
  • An understanding of hypothesis-driven experimentation
  • Working in a GLP environment

Other responsibilities:

  • Interact with other senior members of the research team to ensure appropriate experimental design and analysis
  • Project management and delivery of projects to set timelines
  • Collaboration with the broader team to complete project deliverables
  • Co-ordinating with other groups within the company
  • Mentor/develop the wider scientific team
  • Lab management, ensuring appropriate levels of control over scientific data, equipment, and materials, maintaining appropriate levels of documentation, record keeping, and procedures
  • Health and Safety and GMO risk assessments

Person profile:

  • Innovative and natural problem solver; able to “join the dots” of disparate information
  • Detail-oriented and able to perform precise work in the laboratory
  • Confident and clear presentation of data, verbally and through written reports
  • Effectively manage own time/workload to meet project deliverables with minimal oversight
  • Motivated to learn and master new methods and techniques

The candidate:

This role could suit a Ph.D. qualified candidate with several years of relevant industry experience behind them. Due to the structure of the team, nature of the role, and current growth of the Edinburgh site, we are open to considering candidates with varying levels of industry experience. We would especially welcome applications from individuals with a virology (AAV) background in gene therapy development.  

The opportunity:

This is a unique opportunity to join an exciting, rapidly expanding gene therapy company that has a proven history of developing highly effective, life-changing therapies.

You will be joining a highly skilled team with the opportunity to work at the front end of gene regulation and play a vital role in the development of future gene therapy treatments.

You can expect to receive a competitive salary plus additional benefits including, bonus, life, critical illness, health, pension, cycle to work, onsite gym, on-site café.

For a confidential discussion please contact our retained partner, Keith Tocher at Abercorn Sinclair.

About Abercorn Sinclair

Abercorn Sinclair is a specialist, technical recruitment consultancy based in Edinburgh. We provide permanent, interim, and contract services across the science, technology, and engineering sectors.

 

 

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